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Tetanus Antitoxin

1908

as a prophylactic for Fourth of July
injuries and contaminated wounds

"Every annual compilation that we make of this subject adds to the now conclusive evidence that Tetanus Antitoxin is an almost infallible prophylactic, and that it should be used at the earliest possible moment for every case of penetrating wound caused by Fourth of July injuries."-Ed., Journal A. M. A., 1908, Vol. II, page 42.

"The tetanus mortality has dropped in six years from 406 to 55. We have made extensive inquiries into the treatment received by those injured in Fourth of July accidents, and have yet to learn of a single case in which tetanus developed in a person who had early received a prophylactic dose of antitoxin."-Ed., J. A. M. A., 1908, Vol. II, page 848.

1909

"The following simple rules for the prevention of tetanus are given: "1. Freely incise every wound.

"2. Carefully and thoroughly remove from the wound every particle

of foreign mattter.

"3. Cauterize the wound thoroughly with a 25 per cent solution of phenol (carbolic acid).

"4. Apply a lose wet boric acid pack.

"5. Inject subcutaneously 1500 units of antitetanic serum.

"6. In no case should the wound be closed; it should be allowed to heal by granulation. The dressing and packing should be removed every day.”—Ed., J. A. M. A., 1909, Vol. II, page 954.

"To put the matter in a nutshell, it may be stated dogmatically that the value of Tetanus Antitoxin as a prophylactic agent is very great, and its efficiency nearly absolute. To neglect to use antitoxin as a curative agent is also unwarranted in the light of our present knowledge."-Ed., J. A. M. A., 1909, Vol. II, page 955.

1910

"The use of prophylactic injections of Tetanus Antitoxin in cases of large and contused wounds contaminated with earth or street dirt, is generally recommended as good routine practice."-Busch, in Archiv. für klinische Chirurgie, Band lxxxii, Heft 1.

"Tetanus Antitoxin is effective, and will, in most cases, forestall a fatal issue if injected immediately or very soon after the wound has been incurred. This agency is no longer of doubtful value' or 'in the experimental stage'; indeed, in our belief, this has now been so well demonstrated that the physician neglecting its use would be held legally negligent in the event of any suit.

"Prophylactic doses of Tetanus Antitoxin (1500 units) given immediately upon the injury are almost absolutely effective. Nevertheless, they should be given at any time up to the appearance of the symptoms."-Ed., Boston Med. and Surg. Jour., 1910, Vol. I, page 684.

Mulford's Tetanus Antitoxin, tested according to the standard adopted by the U. S. Pub. Health and Mar. Hos. Serv., is furnished in improved glass syringes by the prominent pharmacists throughout the States.

1500 units (immunizing dose) . . . $2.50
3000 units (therapeutic dose)

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H. K. MULFORD COMPANY, Philadelphia

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BALTIMORE, MD.

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